Advances and Technical Standards in Neurosurgery by A. J. Strong, R. Dardis (auth.), J. D. Pickard, N. Akalan,

By A. J. Strong, R. Dardis (auth.), J. D. Pickard, N. Akalan, C. Di Rocco, V.V. Dolenc, R. Fahlbusch, J. Lobo Antunes, M. Sindou, N. de Tribolet, C. A. F. Tulleken (eds.)

"... the entire chapters of this quantity of Advances and Technical criteria in Neurosurgery are characterized by way of the typical huge and entire dialogue of the topic dealth with, by means of the actual research of the ancient history and through feedback for destiny instructions. Figures, ... tables and particularly whole reference lists, that could hardly ever be present in modern medical journals, extra concur to supply the reader with an exhaustive and stimulating review." kid's frightened procedure 23/2007

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The right panel was acquired several hours after the left, following deterioration and shortly before death. In the left-hand panel, a single event – characterised by an increase in perfusion, decrease in fluorescence, increase in extracellular potassium, and a period of electrical silence – has the characteristics of CSD. The characteristics of the event in the right panel have changed in that fluorescence now increases, but perfusion (LDF ) shows a decrease. The characteristics now correspond more with features of PID rather than CSD in the brain.

J Neurosc 18:3416–3425 36. Mantz J, Cordier J, Giaume C (1993) E¤ects of general anesthetics on intercellular communications mediated by gap junctions between astrocytes in primary culture. Anesthesiology 78:892–901 37. Saito R, Graf R, Hubel K, Taguchi J, Rosner G, Fujita T et al (1995) Halothane, but not alpha-chloralose, blocks potassium-evoked cortical spreading depression in cats. Brain Res 699:109–115 38. Saito R, Graf R, Hubel K, Fujita T, Rosner G, Heiss WD (1997) Reduction of infarct volume by halothane: e¤ect on cerebral blood flow or perifocal spreading depression-like depolarizations.

The characteristics of the event in the right panel have changed in that fluorescence now increases, but perfusion (LDF ) shows a decrease. The characteristics now correspond more with features of PID rather than CSD in the brain. There now appears to be wide recognition of the value of locating detection devices, at the very least for research purposes, near the edge of focal lesions. Recently our group has undertaken a prospective, pilot study designed to detect – or exclude – CSD/PID in patients undergoing emergency craniotomy for traumatic and spontaneous intracranial haematoma [4].

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